Efficacy of oral mucositis in the hamster model induced by 5-fluorouracil (5-FU) plus acetic acid.

<p>A, Changes in oral mucositis area for each treatment group were calculated and plotted over the course of the study. B, Changes in body weight for each treatment group were calculated and plotted over the course of the study. Hamsters received two intraperitoneal injections of 5-FU or saline on days 0 and 2. They were also injected with 10% acetic acid or saline in the left side cheek pouch on day 2. Each point represents the mean ± SD (n = 8–10).