<p>BMDCs were stimulated with SWAP, SEA, Pam3CSK4 and a blank control. The level of IFN-γ(A), IL-10(C) and the ratio of IFN-γ/IL-10(E) produced by naïve CD4<sup>+</sup>T cells primed by TLR2<sup>−/−</sup>-BMDCs or B6 BMDCs. The level of IFN-γ(B), IL-10(D) and the ratio of IFN-γ/IL-10(F) produced by naïve CD4<sup>+</sup>T cells primed by B6 BMDCs pretreated with αPD-L2 antibody. Data are representative result of three independent experiments. Data are presented as the mean±SEM. *<i>P</i><0.05, **<i>P</i><0.01.</p
<p>(<b>A</b>) Freshly isolated CD4+CD25− T-cells (2×10<sup>5</sup>/ml) were stimulated with α-CD3 (0...
<p>(<b>A</b>) The profile of indicated cytokines in the supernatants of PARP-1<sup>−/−</sup> (black ...
<p>IFN-α responses of CD172a<sup>+</sup>-sorted cells stimulated with CpG (10 µg/ml; grey line) or F...
<p>(A) CD4<sup>+</sup> T cells were cocultured with allogeneic mDC or IL-10 DC and incubated with co...
<p>(A, B) CD4<sup>+</sup> or CD8<sup>+</sup> T cells were stimulated in primary culture with allogen...
<p>(<b>A</b>) and (<b>B</b>) Naïve CD4 T cells were cultured in Th17 culture conditions in the prese...
<p>(A, B) CD4<sup>+</sup> or CD8<sup>+</sup> T cells were cultured in primary culture with allogenei...
<p>(a–d) The amount of IFNγ, IL-4, IL-10, and IL-17 secreted into the supernatant was measured by EL...
<p>(<b>A</b>) and (<b>B</b>) Wt mice were immunized with MOG peptide emulsified in CFA. On day 7 pos...
<p>DCs cultured in the absence (filled bars) or presence (open bars) of 5 µg/ml TLR2-blocking antibo...
<p>(A, B) Immature DC were stimulated at day 5 of culture with a maturation cocktail (mDC) or a matu...
<p>Representative FACs plot of peptide specific IFN-γ producing CD8<sup>+</sup> and CD4<sup>+</sup> ...
<p>Naïve T cells cultured with or without IFN-β in Th1-polarizing conditions (10 ng/ml IL-12) (A) or...
<p><b>A</b>) Cytokine production by IFN-DC and IL-4-DC. The amounts of the indicated cytokines were ...
<p>Cells from naïve or 5 week infected draining lymph nodes or from ears were analyzed for IFN-γ, IL...
<p>(<b>A</b>) Freshly isolated CD4+CD25− T-cells (2×10<sup>5</sup>/ml) were stimulated with α-CD3 (0...
<p>(<b>A</b>) The profile of indicated cytokines in the supernatants of PARP-1<sup>−/−</sup> (black ...
<p>IFN-α responses of CD172a<sup>+</sup>-sorted cells stimulated with CpG (10 µg/ml; grey line) or F...
<p>(A) CD4<sup>+</sup> T cells were cocultured with allogeneic mDC or IL-10 DC and incubated with co...
<p>(A, B) CD4<sup>+</sup> or CD8<sup>+</sup> T cells were stimulated in primary culture with allogen...
<p>(<b>A</b>) and (<b>B</b>) Naïve CD4 T cells were cultured in Th17 culture conditions in the prese...
<p>(A, B) CD4<sup>+</sup> or CD8<sup>+</sup> T cells were cultured in primary culture with allogenei...
<p>(a–d) The amount of IFNγ, IL-4, IL-10, and IL-17 secreted into the supernatant was measured by EL...
<p>(<b>A</b>) and (<b>B</b>) Wt mice were immunized with MOG peptide emulsified in CFA. On day 7 pos...
<p>DCs cultured in the absence (filled bars) or presence (open bars) of 5 µg/ml TLR2-blocking antibo...
<p>(A, B) Immature DC were stimulated at day 5 of culture with a maturation cocktail (mDC) or a matu...
<p>Representative FACs plot of peptide specific IFN-γ producing CD8<sup>+</sup> and CD4<sup>+</sup> ...
<p>Naïve T cells cultured with or without IFN-β in Th1-polarizing conditions (10 ng/ml IL-12) (A) or...
<p><b>A</b>) Cytokine production by IFN-DC and IL-4-DC. The amounts of the indicated cytokines were ...
<p>Cells from naïve or 5 week infected draining lymph nodes or from ears were analyzed for IFN-γ, IL...
<p>(<b>A</b>) Freshly isolated CD4+CD25− T-cells (2×10<sup>5</sup>/ml) were stimulated with α-CD3 (0...
<p>(<b>A</b>) The profile of indicated cytokines in the supernatants of PARP-1<sup>−/−</sup> (black ...
<p>IFN-α responses of CD172a<sup>+</sup>-sorted cells stimulated with CpG (10 µg/ml; grey line) or F...