<p><b>A</b> Knockdown and overexpression of dInR in LK neurons produce the same phenotypes when flies are exposed to desiccation (dry starvation). Here the constitutively active dInR (dInR-CA) was used. Both manipulations lead to significantly increased resistance to desiccation, suggesting a malfunction in LK release that decreases diuresis in flies (***p<0.001, n = 120 flies for each genotype from 3 crosses; Log-rank (Mantel-Cox) Test). Note that two different dInR-RNAi lines were tested (a and b). <b>B</b> Feeding, as measured in CAFE assay, is decreased both in flies with dInR knockdown and over expression. Cumulative amount of food eaten over four days is displayed. As a control we used flies with LK neurons hyperpolarized with a const...
(A) Refeeding after 24h starvation increases Dsk transcript in the head of Drosophila. ****p t test....
<p>A) Schematic of selection processes for SR and DR flies. Adult outbred flies were placed under de...
SummaryBackgroundTotal food intake is a function of meal size and meal frequency, and adjustments to...
<p>Neurons are visualized with anti-LK. <b>A–C</b> Monitoring adult ABLKs (Posterior) and adult-spec...
(A) Diagram of ex vivo Ca2+ imaging. Fed or 24-hr–starved adult female flies were dissected and plac...
Behavior and physiology are orchestrated by neuropeptides acting as central neuromodulators and circ...
(A) Knockdown of AMPKα in Lk neurons (Lk-GAL4, n = 32, p = 0.14) abolishes starvation-induced sleep ...
Behavior and physiology are orchestrated by neuropeptides acting as central neuromodulators and circ...
(A and B) Relative expression levels of Gr64f transcripts in DSK deficient files. Depletion of Dsk, ...
Background: Total food intake is a function of meal size and meal frequency, and adjustments to t...
Expression pattern for Lkr−/−>UAS-mCD8::GFP (A), R65C07-GAL4 (C), R67D01-GAL4 (F), and Dilp2-GAL4 (I...
(A) Expression of dMpped in specific neurons in the fly brain. Data was extracted from single cell R...
Ethogram showing percentage of time (A) AkhR-IR>+, (B) n-sybG4>+, and (C) n-sybG4/UAS—AKH-R RNAi mal...
<p><b>A)</b> Diagram illustrating the temporal consumption assay. The time individual flies consumed...
<p>(<b>A</b>) Immunofluorescent detection of mCD8::GFP driven by <i>NP3061-Gal4</i> and <i>NP5286-Ga...
(A) Refeeding after 24h starvation increases Dsk transcript in the head of Drosophila. ****p t test....
<p>A) Schematic of selection processes for SR and DR flies. Adult outbred flies were placed under de...
SummaryBackgroundTotal food intake is a function of meal size and meal frequency, and adjustments to...
<p>Neurons are visualized with anti-LK. <b>A–C</b> Monitoring adult ABLKs (Posterior) and adult-spec...
(A) Diagram of ex vivo Ca2+ imaging. Fed or 24-hr–starved adult female flies were dissected and plac...
Behavior and physiology are orchestrated by neuropeptides acting as central neuromodulators and circ...
(A) Knockdown of AMPKα in Lk neurons (Lk-GAL4, n = 32, p = 0.14) abolishes starvation-induced sleep ...
Behavior and physiology are orchestrated by neuropeptides acting as central neuromodulators and circ...
(A and B) Relative expression levels of Gr64f transcripts in DSK deficient files. Depletion of Dsk, ...
Background: Total food intake is a function of meal size and meal frequency, and adjustments to t...
Expression pattern for Lkr−/−>UAS-mCD8::GFP (A), R65C07-GAL4 (C), R67D01-GAL4 (F), and Dilp2-GAL4 (I...
(A) Expression of dMpped in specific neurons in the fly brain. Data was extracted from single cell R...
Ethogram showing percentage of time (A) AkhR-IR>+, (B) n-sybG4>+, and (C) n-sybG4/UAS—AKH-R RNAi mal...
<p><b>A)</b> Diagram illustrating the temporal consumption assay. The time individual flies consumed...
<p>(<b>A</b>) Immunofluorescent detection of mCD8::GFP driven by <i>NP3061-Gal4</i> and <i>NP5286-Ga...
(A) Refeeding after 24h starvation increases Dsk transcript in the head of Drosophila. ****p t test....
<p>A) Schematic of selection processes for SR and DR flies. Adult outbred flies were placed under de...
SummaryBackgroundTotal food intake is a function of meal size and meal frequency, and adjustments to...