hERG channel expression suppressed by BmKKx2 in erythroid differentiation of K562 cells.

<p>(A) γ-globin expression in K562 cells during the differentiation with or without BmKKx2 shown by quantitative real-time PCR. (B) hERG channel expression in K562 cells during the differentiation process with or without BmKKx2 shown by quantitative real-time PCR. **<i>p</i><0.01 (Student’s <i>t</i>-test). Symbols and associated error bars represent means ± SD for three independent experiments (C) hERG and γ-globin expression in K562 cells with or without BmKKx2 tested by the western blotting analysis. Both HERG1 and HERG1B isoforms were detected [24].