Uptake of C2IN-C3lim into differentiating osteoclasts and morhophological changes caused by C2IN-C3lim.

<p>RAW264.7 cells which were grown in the presence of RANKL to induce differentiation to osteoclasts. Cells were left untreated for control (A) or treated with C2IN-C3lim (2 µg/mL) at day 0 and 2 (B and C). At day 5, osteoclasts were stained for actin (red), nuclei (blue) and C3 (green) and cells analyzed by phase contrast microscopy (left row) and fluorescence microscopy.