<p><b>A.</b> GLP-1 levels in mouse plasma. The male <i>KKay</i> mice (n = 10/group) were treated as in Fig. 6A. Blood samples were collected 30 min after administration of glucose and plasma GLP-1 levels were measured. <b>B.</b> GLP-1 secretion by STC-1 cells. STC-1 cells were treated with various concentration of Diapin for 2 hours and the supernatants were collected for GLP-1 measurement. *<i>P</i><0.05, compared with that in the absence of Diapin.</p
Dipeptidyl peptidase (DPP)-4 and neprilysin (NEP) rapidly degrade glucagon-like peptide 1 (GLP-1) in...
Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) potently augm...
Glucagon-like peptide-1 (GLP-1), a future treatment for type 2 diabetes, is efficiently degraded by ...
<p><b>A.</b> Insulin levels in mouse plasma. The fasted male <i>KKay</i> mice were randomly divided ...
<p>(A) Male <i>KKay</i> diabetic mice and (<b>B</b>) adult male C57BL/6J mice under non-fasting cond...
<p><b>A.</b> Effect of Diapin on blood glucose. The mice were fasted overnight and orally loaded wit...
<p>After oral loading of Diapin (Δ, 0.5 mg/g; ▪, 1 mg/g) by gavage, OGTT was performed in male (<b>A...
<p>The mice were orally given vehicle in the control group (n = 10) and Diapin (1 mg/g, n = 10) in t...
<p>Male <i>KKay</i> diabetic mice were randomly divided into control and treated groups. In control ...
The prevalence of type 2 diabetes (T2D) is rapidly increasing worldwide. Effective therapies, such a...
<p>Plasma GLP-1 levels were significantly higher in mice treated with PSN632408 and sitagliptin comb...
<p>In <i>glut2<sup>+/+</sup></i> and <i>glut2<sup>−/−</sup></i> mice receiving an oral glucose gavag...
GLP-1 on insulin secretion, insulin sensitivity, and glucose effectiveness in mice. Am. J. Physiol. ...
<p><i>Sglt1<sup>+/+</sup></i> and <i>sglt1<sup>−/−</sup></i> mice were challenged with an oral gluco...
<p>(A) Serum GLP-1 and GIP levels under free-feeding condition. Values are means ±S.E.M. (n = 6). *<...
Dipeptidyl peptidase (DPP)-4 and neprilysin (NEP) rapidly degrade glucagon-like peptide 1 (GLP-1) in...
Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) potently augm...
Glucagon-like peptide-1 (GLP-1), a future treatment for type 2 diabetes, is efficiently degraded by ...
<p><b>A.</b> Insulin levels in mouse plasma. The fasted male <i>KKay</i> mice were randomly divided ...
<p>(A) Male <i>KKay</i> diabetic mice and (<b>B</b>) adult male C57BL/6J mice under non-fasting cond...
<p><b>A.</b> Effect of Diapin on blood glucose. The mice were fasted overnight and orally loaded wit...
<p>After oral loading of Diapin (Δ, 0.5 mg/g; ▪, 1 mg/g) by gavage, OGTT was performed in male (<b>A...
<p>The mice were orally given vehicle in the control group (n = 10) and Diapin (1 mg/g, n = 10) in t...
<p>Male <i>KKay</i> diabetic mice were randomly divided into control and treated groups. In control ...
The prevalence of type 2 diabetes (T2D) is rapidly increasing worldwide. Effective therapies, such a...
<p>Plasma GLP-1 levels were significantly higher in mice treated with PSN632408 and sitagliptin comb...
<p>In <i>glut2<sup>+/+</sup></i> and <i>glut2<sup>−/−</sup></i> mice receiving an oral glucose gavag...
GLP-1 on insulin secretion, insulin sensitivity, and glucose effectiveness in mice. Am. J. Physiol. ...
<p><i>Sglt1<sup>+/+</sup></i> and <i>sglt1<sup>−/−</sup></i> mice were challenged with an oral gluco...
<p>(A) Serum GLP-1 and GIP levels under free-feeding condition. Values are means ±S.E.M. (n = 6). *<...
Dipeptidyl peptidase (DPP)-4 and neprilysin (NEP) rapidly degrade glucagon-like peptide 1 (GLP-1) in...
Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) potently augm...
Glucagon-like peptide-1 (GLP-1), a future treatment for type 2 diabetes, is efficiently degraded by ...