<p>MTT assay was performed on human normal fibroblast cells treated with [(dmb)<sub>2</sub>Ru(obip)Ru(dmb)<sub>2</sub>]<sup>4</sup> A), human cervical cancer Hela cells treated with [(dmb)<sub>2</sub>Ru(obip)Ru(dmb)<sub>2</sub>]<sup>4+</sup> at gradient concentrations B), Hela cells treated with a clinical chemotherapeutic cisplatin C), K562 cells treated with [(dmb)<sub>2</sub>Ru(obip)Ru(dmb)<sub>2</sub>]<sup>4</sup> D) and K562 cells treated with cisplatin respectively at gradient concentrations. The inhibition ratio was collected as the average of triplicate wells relative to that of the untreated wells. Result shown here was the representative one among three independent experiments. Data were presented as mean +/- S.E.M.* means P < 0.0...
A series of cis-dichloroplatinum(II) 2,3-diaminopropionamide complexes synthesised as potential imag...
Discovery of the metallopharmaceutical cisplatin and its use in antitumour therapy has initiated the...
Target identification and mechanistic studies of cytotoxic agents are challenging processes that are...
Platinum complexes, such as cisplatin, are well known for exhibiting anticancer activity in a variet...
<p>Λ-[Ru(phen)<sub>2</sub>(<i>p-</i>HPIP)]<sup>2+</sup> and Δ-[Ru(phen)<sub>2</sub>(<i>p-</i>HPIP)]<...
<p>Cells were treated with the tested compounds for 24 h; measurements were performed in triplicate,...
Triple-negative breast cancer (TNBC) is a highly aggressive breast cancer subtype. The high rate of ...
Introduction: Combination therapy to treat cancer have been demanded due to the complexity of the di...
Two <i>p</i>-cymenerutheniumchlorido complexes with thiourea derivative of 7-chloroquinoline (<b>C1<...
In recent years, rııtheniıım (II) comp\exes have increasinglv attracted the interest of researchers ...
Two new Ru(II) complexes containing O, O-chelated ligands, Ru(dip)2(SA) (Ru-1) and Ru(dmp)2(SA) (Ru-...
<p>The data were obtained by the MTT assay against human lung carcinoma A549, cervix epithelial carc...
The new monofunctional Ru(II)-arene complex [(η6-arene)Ru(II)(en)Cl]+, where en = 1,2-diaminoethane ...
The synthesis, characterization and antiproliferative activity of the bimetallic Ru-Zn complex [RuC...
<p> <b><i>vitro</i></b><b> cytotoxicity against selected cancer cell lines for complexes 4–6 and </b...
A series of cis-dichloroplatinum(II) 2,3-diaminopropionamide complexes synthesised as potential imag...
Discovery of the metallopharmaceutical cisplatin and its use in antitumour therapy has initiated the...
Target identification and mechanistic studies of cytotoxic agents are challenging processes that are...
Platinum complexes, such as cisplatin, are well known for exhibiting anticancer activity in a variet...
<p>Λ-[Ru(phen)<sub>2</sub>(<i>p-</i>HPIP)]<sup>2+</sup> and Δ-[Ru(phen)<sub>2</sub>(<i>p-</i>HPIP)]<...
<p>Cells were treated with the tested compounds for 24 h; measurements were performed in triplicate,...
Triple-negative breast cancer (TNBC) is a highly aggressive breast cancer subtype. The high rate of ...
Introduction: Combination therapy to treat cancer have been demanded due to the complexity of the di...
Two <i>p</i>-cymenerutheniumchlorido complexes with thiourea derivative of 7-chloroquinoline (<b>C1<...
In recent years, rııtheniıım (II) comp\exes have increasinglv attracted the interest of researchers ...
Two new Ru(II) complexes containing O, O-chelated ligands, Ru(dip)2(SA) (Ru-1) and Ru(dmp)2(SA) (Ru-...
<p>The data were obtained by the MTT assay against human lung carcinoma A549, cervix epithelial carc...
The new monofunctional Ru(II)-arene complex [(η6-arene)Ru(II)(en)Cl]+, where en = 1,2-diaminoethane ...
The synthesis, characterization and antiproliferative activity of the bimetallic Ru-Zn complex [RuC...
<p> <b><i>vitro</i></b><b> cytotoxicity against selected cancer cell lines for complexes 4–6 and </b...
A series of cis-dichloroplatinum(II) 2,3-diaminopropionamide complexes synthesised as potential imag...
Discovery of the metallopharmaceutical cisplatin and its use in antitumour therapy has initiated the...
Target identification and mechanistic studies of cytotoxic agents are challenging processes that are...