Prdx6, PPIA and CD147 were overexpressed in human OSCCs.

<p>A, Representative immunohistochemical staining of Prdx6, PPIA and CD147 in human oral cancer tissue (right) compared with normal oral mucosa (left) (Scale bars = 100 umol). B, Quantatitive of histoscore of Prdx6, PPIA and CD147 expression in normal oral mucosa, oral epithelial dysplasia and human oral cancer, Prdx6, PPIA and CD147 levels in OSCC was significant higher when compared with oral epithelial dysplasia and/or normal oral mucosa (Mean ± SEM; *, <i>P</i><0.05; **, <i>P</i><0.01; ***, <i>P</i><0.001; One-way ANOVA). C, Prdx6, PPIA and CD147 were not significantly associated with lymph node status (Quantification using Aperio nuclear quantification software, and statistics using Graph Pad Prism 5. Mean ± SEM; *, <i>P</i><0.05; Mann–Whitney U test and One-way ANOVA).