Model highlighting differentially expressed genes involved in fuel utilization and heat generation in BAT during hibernation.

<p>The role of the gene products in various metabolic processes in a brown adipocyte is shown. Genes with abbreviations in red meet the criteria for differential expression showing highest mRNA levels during the hibernation phases of torpor or interbout arousal. Abbreviations of genes that are not differentially expressed but are highly expressed, and/or tissue-specific genes in BAT, are shown in black. Molecules that serve as sources of fuel are labeled in green. Gene name abbreviations are defined in Table S1. Abbreviations: Ad, adenosine; NE, norepinepherine; NEFA, non-esterified fatty acids; TAG, triacylglycerol.