Direct effects of miR-17-5p on h-ERG trafficking in h-ERG-expressing HEK293 cells.

<p>(a) Effects of exogenously applied miR-17-5p mimic on h-ERG trafficking assessed by Western blot analysis. miR-17-5p-I: miR-17-5p inhibitor (co-transfected with miR-17-5p mimic); MT miR-17-5p: mutant miR-17-5p. ***<i>P</i><0.001 miR-17-5p <i>vs</i> Control; ^###<i>P</i><0.001 miR-17-5p-I <i>vs</i> miR-17-5p; n=6; (b) Effects of miR-17-5p-I on oxidative stress-induced trafficking disruption of h-ERG. ***<i>P</i><0.001 H₂O₂<i>vs</i> Control; ^###<i>P</i><0.001 miR-17-5p-I <i>vs</i> H₂O₂; n=5.