Comparison of different human and mouse CPE gene expression analysis.

<p>Comparison of our (bold printed) human and mouse CPE gene expressions, functional annotation and specifically expressed genes with those of previously published human and mouse CPE transcriptomes.</p><p>¹ Total numbers of genes in the High Expression (>90th percentile (P)) sub-datasets.</p><p>² Comparison of the genes in the >90th P of different datasets from literature with our “Human and Mouse High CPE expression (>90^th P) sub-datasets” per species. The number and percentage of overlap is given.</p><p>³ Comparison of the functional annotation (Funct. Annot); h-s = highly similar.</p><p>⁴ Comparison with mouse specific functions. Metab = Metabolism: metabolic function and diseases, including carbohydrate metabolism, lipid metabolism, aciduria, mitochondrial disorder, hyperglycemia, hypoglycemia and amyloidosis. Dev = Development: More extensive list of developmental functions, including development of eye, cornea, cortex, brain and embryo-size. Clath = Clathrin: Clathrin-mediated endocytosis signaling.</p><p>⁵ Comparison with specifically expressed genes. We identified three genes that we specifically expressed in mouse CPE compared to the human CPE, namely <i>ACE</i>, <i>PON1</i> and <i>TRIM3</i>. We subdivided the gene expression data of human and mouse CPE from literature also in groups based on percentiles (P): high (H) (>90^th P), moderate (M) (50–90^th P), low (L) (10–50^th P) and very low (VL) (<10^th P) and we looked in which of these groups the three genes were expressed in the gene expression databases from literature. Sometimes, no data were available for a gene (indicated with “x”).