<p>Adult heart mRNA was collected from <i>Gata6<sup>fl/fl-βMHC-cre</sup></i> mice and compared against mRNA from <i>Gata6<sup>fl/fl</sup></i> to generate Affymetrix expression arrays of genes that were specifically changed in with deletion of <i>Gata6</i>. And identical protocol was used to analyze genes changed with deletion of <i>Gata4</i> from the heart. Afterwards the two arrays sets were cross compared to examine genes that might be more specific to GATA-4 or GATA-6 regulation, which is represented as the column “difference” showing normalized expression results. The values represent the difference between normalized GATA-4 expression over normalized GATA-6 expression, both of which are corrected to the common cre control and each resp...
GATA-6 has been implicated in the regulation of myocardial differentiation during cardiogenesis. To ...
<p>mRNA expression of tRNA splicing endonuclease 3 (Tsen15; <b>panel a</b>), Growth arrest specific ...
<p>Little is known about the underlying regulatory network responsible for the development<br>of the...
<p>Adult heart mRNA was collected from the indicated lines of adult mice and subjected to qRT-PCR to...
<p>Whole genome microarray expression analysis was performed on RNA isolated from whole adult mouse ...
<p><b>(A)</b> Assessment of ventricular mRNA expression by quantitative real-time PCR of atrial natr...
The transcriptional code that programs cardiac hypertrophy involves the zinc finger-containing DNA b...
<p>Microarray was performed on LV myocardial tissue from 3 mice per genotype, one array per mouse. D...
<p>Number of differentially expressed genes at different fold-change cutoffs with false discovery ra...
The transcription factors GATA4, GATA5 and GATA6 play important roles in heart muscle differentiatio...
<p>The graph shows immunohistological quantitation of capillaries in the left ventricle normalized t...
Members of the GATA family of transcription factors are evolutionary conserved DNA-binding proteins ...
<p>(<b>A</b>) Schematic of microarray loop experiment. RNA isolated from G<sub>0</sub> MB was analyz...
<p>Donor hearts were treated and transplanted into syngeneic C57BL/6 recipient mice. At day 2 post t...
The morphological and cellular changes observed during embryonic development are mainly caused by a ...
GATA-6 has been implicated in the regulation of myocardial differentiation during cardiogenesis. To ...
<p>mRNA expression of tRNA splicing endonuclease 3 (Tsen15; <b>panel a</b>), Growth arrest specific ...
<p>Little is known about the underlying regulatory network responsible for the development<br>of the...
<p>Adult heart mRNA was collected from the indicated lines of adult mice and subjected to qRT-PCR to...
<p>Whole genome microarray expression analysis was performed on RNA isolated from whole adult mouse ...
<p><b>(A)</b> Assessment of ventricular mRNA expression by quantitative real-time PCR of atrial natr...
The transcriptional code that programs cardiac hypertrophy involves the zinc finger-containing DNA b...
<p>Microarray was performed on LV myocardial tissue from 3 mice per genotype, one array per mouse. D...
<p>Number of differentially expressed genes at different fold-change cutoffs with false discovery ra...
The transcription factors GATA4, GATA5 and GATA6 play important roles in heart muscle differentiatio...
<p>The graph shows immunohistological quantitation of capillaries in the left ventricle normalized t...
Members of the GATA family of transcription factors are evolutionary conserved DNA-binding proteins ...
<p>(<b>A</b>) Schematic of microarray loop experiment. RNA isolated from G<sub>0</sub> MB was analyz...
<p>Donor hearts were treated and transplanted into syngeneic C57BL/6 recipient mice. At day 2 post t...
The morphological and cellular changes observed during embryonic development are mainly caused by a ...
GATA-6 has been implicated in the regulation of myocardial differentiation during cardiogenesis. To ...
<p>mRNA expression of tRNA splicing endonuclease 3 (Tsen15; <b>panel a</b>), Growth arrest specific ...
<p>Little is known about the underlying regulatory network responsible for the development<br>of the...