Effects of rs1836882 on NOX4 and <i>HNF3γ</i> expression in PBMC treated with different serums.

<p>Upper panel: Representative western blots of alterations in NOX4, HNF3γ and β-actin protein levels in PBMC after different treatments. G1: Control group; G2: SHC group; G3: NOX4 group; G4: SHC+NOX4 group; G5: HNF3γ group; <b>G6</b>: SHC+ HNF3γ group; <b>G7</b>: HNF3γ over-expression group; and <b>G8</b>: SHC+ HNF3γ over-expression group. <b>A</b> and <b>B</b>: Genotype-dependent changes of NOX4 gene mRNA and protein levels, respectively. <b>C</b> and <b>D</b>: Genotype-dependent changes of <i>HNF3γ</i> gene mRNA and protein levels, respectively. * <i>P</i><0.05 <i>vs</i>. control group; ▲ <i>P</i><0.05 <i>vs</i>. the other two genotypes within the same group. PBMC: peripheral blood mononuclear cells; SHC: serum from high caloric intake group; SLC: serum from low caloric intake group.