<p>Data are given as OR (95% CI) followed by <i>p</i>-value. Elevated mtDNA level represents NADH dehydrogenase 1 DNA copy number of ≥3,200 copies/µl plasma.</p><p><sup>a</sup> Includes MICU and cardiac ICU patients.</p><p><sup>b</sup> Includes surgical ICU, trauma ICU, and neurological ICU patients.</p><p><sup>c</sup> Multivariate models in both cohorts were adjusted for age, gender, and race/ethnicity, with additional adjustments where indicated.</p
Objectives: We assessed whether at admission plasma circulating cell free mitochondrial DNA (ccf-mtD...
<p>Plasma mtDNA concentrations presented as median values (line across the boxes), IQR (limits of th...
Background: Mitochondrial DNA copy number (mtDNA-CN) has been associated with a variety of aging-rel...
<p>Elevated mtDNA level represents NADH dehydrogenase 1 DNA copy number of ≥3,200 copies/µl plasma.<...
<p><sup>a</sup> Includes MICU and cardiac ICU patients.</p><p><sup>b</sup><i>p</i>-Value using risk ...
<p>Boxplots comparing measures of cell-free mtDNA level (mtDNA [NADH dehydrogenase 1] expressed as c...
<p>Kaplan-Meier estimates of survival for patients who had plasma mtDNA levels ≥3,200 copies/µl (<i>...
Compared with high mononuclear mtDNA copy number, those with low mtDNA copy number had a higher rate...
Mitochondrial DNA (mtDNA) is a critical activator of inflammation and the innate immune system. Howe...
<p>Plasma mtDNA concentrations presented as median values (line across the boxes), IQR (limits of th...
<p>Comparisons of receiver operating characteristic (ROC) curves for a clinical model (including age...
<p>Plasma mtDNA concentrations presented as median values (line across the boxes), IQR (limits of th...
Several predictive biomarkers for coronavirus disease (COVID-19)-associated mortality in critically ...
Background: Mitochondrial dysfunction may be causally related to the pathogenesis o...
<p>Relationships between mtDNA copy number and disease severity in A3243G patients.</p
Objectives: We assessed whether at admission plasma circulating cell free mitochondrial DNA (ccf-mtD...
<p>Plasma mtDNA concentrations presented as median values (line across the boxes), IQR (limits of th...
Background: Mitochondrial DNA copy number (mtDNA-CN) has been associated with a variety of aging-rel...
<p>Elevated mtDNA level represents NADH dehydrogenase 1 DNA copy number of ≥3,200 copies/µl plasma.<...
<p><sup>a</sup> Includes MICU and cardiac ICU patients.</p><p><sup>b</sup><i>p</i>-Value using risk ...
<p>Boxplots comparing measures of cell-free mtDNA level (mtDNA [NADH dehydrogenase 1] expressed as c...
<p>Kaplan-Meier estimates of survival for patients who had plasma mtDNA levels ≥3,200 copies/µl (<i>...
Compared with high mononuclear mtDNA copy number, those with low mtDNA copy number had a higher rate...
Mitochondrial DNA (mtDNA) is a critical activator of inflammation and the innate immune system. Howe...
<p>Plasma mtDNA concentrations presented as median values (line across the boxes), IQR (limits of th...
<p>Comparisons of receiver operating characteristic (ROC) curves for a clinical model (including age...
<p>Plasma mtDNA concentrations presented as median values (line across the boxes), IQR (limits of th...
Several predictive biomarkers for coronavirus disease (COVID-19)-associated mortality in critically ...
Background: Mitochondrial dysfunction may be causally related to the pathogenesis o...
<p>Relationships between mtDNA copy number and disease severity in A3243G patients.</p
Objectives: We assessed whether at admission plasma circulating cell free mitochondrial DNA (ccf-mtD...
<p>Plasma mtDNA concentrations presented as median values (line across the boxes), IQR (limits of th...
Background: Mitochondrial DNA copy number (mtDNA-CN) has been associated with a variety of aging-rel...