<p>(A) The blood glucose changes pre- and post -i.v. injection. (B) The plasma insulin levels. (C) The insulin-resistance coefficient. HOMA IR = fasting plasma insulin (µU/ml)×fasting plasma glucose (mmol/l)/22.5. All data were expressed as the mean ± S.E.M of 4–8 mice/group. *p<0.05, **p<0.01 (compared with the HFDN group). <sup>#</sup>p<0.05, <sup>##</sup>p<0.01 (compared with DMN group), <sup>+</sup>p<0.05 (compared with DML group)</p
Abstract Background: Diabetes mellitus was induced, when the body doesn’t produce enough insulin ...
Insulin resistance and declining insulin productiondefine a spectrum of metabolic diseases afflictin...
<p>(A) Blood glucose determined by OGTT after oral administration of glucose (2%). (B) Area under cu...
<p>Oral glucose tolerance tests and insulin sensitivity tests are shown in left and right panels, re...
<p>(A) Cumulative food intake levels of 0–1h, 0–2h, 0–24h. (B) The body weight changes pre- and post...
AIMS/HYPOTHESIS:The actions of peripherally administered nesfatin-1 on glucose homeostasis remain co...
The actions of peripherally administered nesfatin-1 on glucose homeostasis remain controversial. The...
<p>Mice received subcutaneous infusion of saline (control) or nesfatin-1 (2.5 pmol/mouse/hour). Insu...
<p>(A, C) Immunofluorescent staining for GLUT4. Immunofluorescent staining was performed using speci...
<p>Mice were fed high fat diet for 8 weeks, and then received subcutaneous infusion of saline (contr...
<p>Immunofluorescent staining was performed using specific antibody against GLUT4 (red) in skeletal ...
<p>(<b>A</b>) Fold change in blood glucose measured during an oral gavage study in mice gavaged with...
Nesfatin-1 is an anorexigenic peptide involved in energy homeostasis. Recently, nesfatin-1 was repor...
Nesfatin-1 is a peptide secreted by peripheral tissues, central and peripheral nervous system. It is...
<p>(A) Mice were fed high fat diet for 8 weeks, then received subcutaneous infusion of saline (contr...
Abstract Background: Diabetes mellitus was induced, when the body doesn’t produce enough insulin ...
Insulin resistance and declining insulin productiondefine a spectrum of metabolic diseases afflictin...
<p>(A) Blood glucose determined by OGTT after oral administration of glucose (2%). (B) Area under cu...
<p>Oral glucose tolerance tests and insulin sensitivity tests are shown in left and right panels, re...
<p>(A) Cumulative food intake levels of 0–1h, 0–2h, 0–24h. (B) The body weight changes pre- and post...
AIMS/HYPOTHESIS:The actions of peripherally administered nesfatin-1 on glucose homeostasis remain co...
The actions of peripherally administered nesfatin-1 on glucose homeostasis remain controversial. The...
<p>Mice received subcutaneous infusion of saline (control) or nesfatin-1 (2.5 pmol/mouse/hour). Insu...
<p>(A, C) Immunofluorescent staining for GLUT4. Immunofluorescent staining was performed using speci...
<p>Mice were fed high fat diet for 8 weeks, and then received subcutaneous infusion of saline (contr...
<p>Immunofluorescent staining was performed using specific antibody against GLUT4 (red) in skeletal ...
<p>(<b>A</b>) Fold change in blood glucose measured during an oral gavage study in mice gavaged with...
Nesfatin-1 is an anorexigenic peptide involved in energy homeostasis. Recently, nesfatin-1 was repor...
Nesfatin-1 is a peptide secreted by peripheral tissues, central and peripheral nervous system. It is...
<p>(A) Mice were fed high fat diet for 8 weeks, then received subcutaneous infusion of saline (contr...
Abstract Background: Diabetes mellitus was induced, when the body doesn’t produce enough insulin ...
Insulin resistance and declining insulin productiondefine a spectrum of metabolic diseases afflictin...
<p>(A) Blood glucose determined by OGTT after oral administration of glucose (2%). (B) Area under cu...