<p>Transcription of p<i>Tktl1-2467+25</i> was measured in embryos in which DNA synthesis was inhibited by treatment with aphidicolin. Experiments were performed three times and the results are presented as means ± SEM. Asterisks indicate significant differences (Student's <i>t</i>-test; <i>P</i><0.05).</p
Cloned genomic DNA for human histone H1, H3 and H4 genes has been used to determine the effects of γ...
Three hours following X-irradiation of chick embryos with doses of 4 and 8 Gy the in vitro incorpora...
A highly reproducible technique combining measurements of specific radioactivity and amino acid anal...
The effects of aphidicolin - a powerful inhibitor of DNA polymerase alpha and of DNA replication - o...
Mosaicism is the most important limitation for one-step gene editing in embryos by CRISPR/Cas9 becau...
<p>(a) Egg extracts were mock- or Chk1-depleted and aliquots analyzed by western blotting using an a...
<p>(A) Experimental setup. Proliferating HEL fibroblasts were treated with aphidicolin (Aph) or hydr...
In vivo in mammalian cells, ultraviolet-induced unscheduled DNA synthesis was less sensitive to aphi...
<p>Plasmids (200 ng/µl) were microinjected into the male pronuclei of one-cell-stage embryos and the...
<p>(a) Sperm nuclei were added to egg extracts in the presence of [α-<sup>32</sup>P]-dATP with or wi...
AbstractBy inhibiting the α-like DNA polymerase, and therefore nuclear DNA synthesis, aphidicolin in...
AbstractZygotic gene activation (ZGA) definitely occurs by the 2-cell stage in the mouse embryo. Ana...
Aphidicolin is a tetracyclic diterpinoid fungal antibiotic which inhibits DNA synthesis in eukaryoti...
DNA synthesis in epimastigote forms of Trypanosoma cruzi was studied autoradiographically by incorpo...
Cell synchronization is often achieved by transient inhibition of DNA replication. When cultured in ...
Cloned genomic DNA for human histone H1, H3 and H4 genes has been used to determine the effects of γ...
Three hours following X-irradiation of chick embryos with doses of 4 and 8 Gy the in vitro incorpora...
A highly reproducible technique combining measurements of specific radioactivity and amino acid anal...
The effects of aphidicolin - a powerful inhibitor of DNA polymerase alpha and of DNA replication - o...
Mosaicism is the most important limitation for one-step gene editing in embryos by CRISPR/Cas9 becau...
<p>(a) Egg extracts were mock- or Chk1-depleted and aliquots analyzed by western blotting using an a...
<p>(A) Experimental setup. Proliferating HEL fibroblasts were treated with aphidicolin (Aph) or hydr...
In vivo in mammalian cells, ultraviolet-induced unscheduled DNA synthesis was less sensitive to aphi...
<p>Plasmids (200 ng/µl) were microinjected into the male pronuclei of one-cell-stage embryos and the...
<p>(a) Sperm nuclei were added to egg extracts in the presence of [α-<sup>32</sup>P]-dATP with or wi...
AbstractBy inhibiting the α-like DNA polymerase, and therefore nuclear DNA synthesis, aphidicolin in...
AbstractZygotic gene activation (ZGA) definitely occurs by the 2-cell stage in the mouse embryo. Ana...
Aphidicolin is a tetracyclic diterpinoid fungal antibiotic which inhibits DNA synthesis in eukaryoti...
DNA synthesis in epimastigote forms of Trypanosoma cruzi was studied autoradiographically by incorpo...
Cell synchronization is often achieved by transient inhibition of DNA replication. When cultured in ...
Cloned genomic DNA for human histone H1, H3 and H4 genes has been used to determine the effects of γ...
Three hours following X-irradiation of chick embryos with doses of 4 and 8 Gy the in vitro incorpora...
A highly reproducible technique combining measurements of specific radioactivity and amino acid anal...