<p>Measurements of cochlear lengths reveal that <i>Sfswap<sup>Tg/Tg</sup>, Jag1<sup>+/−</sup></i> mutants are significantly shorter than <i>Sfswap<sup>Tg/Tg</sup></i> or <i>Jag1<sup>+/−</sup></i> mutants. Similarly, at the base and mid, <i>Sfswap<sup>Tg/Tg</sup>, Jag1<sup>+/−</sup></i> mutants have significantly fewer outer hair cells (OHC) than <i>Sfswap<sup>Tg/Tg</sup></i> or <i>Jag1<sup>+/−</sup></i> mutants alone.</p
<p>(A-B”‘) The outgrowth of type II SGN afferents was analyzed by immunocytochemistry in <i>Prickle1...
<p>(A) There was no significant difference in temporal bones between mutant and wild-type mice at P1...
<p>(A–C) Cochlear tissue from adult animals was immunostained and then imaged as a flat-mount by con...
<p>The number of hair cells in each row per 200 µm was collected at the apex, mid and base in P0 coc...
<p>(A, B): Paint fills of E15.5 wild-type, <i>Sfswap<sup>Tg/Tg</sup></i>, compound mutant (<i>Sfswap...
Recent studies have demonstrated that the Notch signaling pathway regulates the differentiation of s...
<p>(A): Cochleas from E13.5 <i>Sfswap<sup>Tg/Tg</sup></i> and wild-type mice co-stained with antibod...
<div><p>Lectin staining of whole-mount cochlea at E16.5.</p><p>(A) Normal patterning in wild-type co...
<p>(A) Scanning electron microscopy (SEM) views of the cochlea at P8: an overview of the apical turn...
<p>SEM images showing stereocilial bundles of outer hair cells in the mid-basal turn in wild-type at...
<p>Cochleas were stained with phalloidin, which binds to filamentous actin (red) and anti-prestin an...
<p>Cytocochleograms indicate percentage of outer (OHC) and inner (IHC) hair-cell loss as a function ...
<p>Higher magnifications of SEM images showing stereocilia bundles of outer hair cells in wild-type ...
<p><b>A-D</b>) High magnification of organ of Corti showing immunohistochemistry for BDNF (red, hair...
AbstractRecent studies have demonstrated that the Notch signaling pathway regulates the differentiat...
<p>(A-B”‘) The outgrowth of type II SGN afferents was analyzed by immunocytochemistry in <i>Prickle1...
<p>(A) There was no significant difference in temporal bones between mutant and wild-type mice at P1...
<p>(A–C) Cochlear tissue from adult animals was immunostained and then imaged as a flat-mount by con...
<p>The number of hair cells in each row per 200 µm was collected at the apex, mid and base in P0 coc...
<p>(A, B): Paint fills of E15.5 wild-type, <i>Sfswap<sup>Tg/Tg</sup></i>, compound mutant (<i>Sfswap...
Recent studies have demonstrated that the Notch signaling pathway regulates the differentiation of s...
<p>(A): Cochleas from E13.5 <i>Sfswap<sup>Tg/Tg</sup></i> and wild-type mice co-stained with antibod...
<div><p>Lectin staining of whole-mount cochlea at E16.5.</p><p>(A) Normal patterning in wild-type co...
<p>(A) Scanning electron microscopy (SEM) views of the cochlea at P8: an overview of the apical turn...
<p>SEM images showing stereocilial bundles of outer hair cells in the mid-basal turn in wild-type at...
<p>Cochleas were stained with phalloidin, which binds to filamentous actin (red) and anti-prestin an...
<p>Cytocochleograms indicate percentage of outer (OHC) and inner (IHC) hair-cell loss as a function ...
<p>Higher magnifications of SEM images showing stereocilia bundles of outer hair cells in wild-type ...
<p><b>A-D</b>) High magnification of organ of Corti showing immunohistochemistry for BDNF (red, hair...
AbstractRecent studies have demonstrated that the Notch signaling pathway regulates the differentiat...
<p>(A-B”‘) The outgrowth of type II SGN afferents was analyzed by immunocytochemistry in <i>Prickle1...
<p>(A) There was no significant difference in temporal bones between mutant and wild-type mice at P1...
<p>(A–C) Cochlear tissue from adult animals was immunostained and then imaged as a flat-mount by con...