Survival of C57BL/6 mice vaccinated against Pks domains and challenged with <i>M. ulcerans</i> 1615.

<p>Ten mice/group were challenged 6 weeks after the protein boost with 10⁵ AFB of <i>M. ulcerans</i> 1615 and subsequently monitored for 112 days for footpad swelling after <i>M. ulcerans</i> 1615 infection. Animals were euthanized when footpad swelling exceeded 4 mm. Figure shows the percentage of surviving mice during the 112 day follow-up. A: Survival curves of unvaccinated (ctrl) mice or mice vaccinated with ACP1, ACP2, ACP3, ATac1, ATac2 or <i>M. bovis</i> BCG. B: Survival curves of unvaccinated (ctrl) mice or mice vaccinated with ATp, ER, KR A, KS, Ag85A or <i>M. bovis</i> BCG.