<p>Abbreviations: Feno; fenofibrate, TC; total cholesterol, HDL-C; high density lipoprotein-cholesterol, TG; triacylglycerol, VEGFR12; VEGFR-1 and –2 inhibition.</p><p><i>P</i><0.01,</p><p><i>P</i><0.001 compared with <i>db/m</i>, <i>db/m</i>+VEGFR12, and <i>db/m</i>+VEGFR12+Feno groups.</p><p><i>P</i><0.05 compared with <i>db/db</i> and <i>db/db</i>+VEGFR12 groups.</p
<p>WT and PPARα KO mice were on a high fat diet for 6 weeks and treated with fenofibrate (FF) or bil...
1<p>Two-way ANOVA and Tukey contrasts were performed to compare differences among the groups of LLC-...
(A) Body weight. (B) Body weight gain. (C) Subcutaneous and epididymal fat mass (g/100 g body weight...
<p><i>A:</i> Body weight gain relative to weight at day 0 for mice given different diets and treatme...
<p>Tactile threshold (A) and motor conduction latency of the sciatic nerves (B) in <i>db/m</i> and <...
The peroxisome proliferator-activated receptor alpha (PPARα) activator fenofibrate efficiently decre...
The peroxisome proliferator-activated receptor alpha (PPAR alpha) activator fenofibrate efficiently ...
Serum concentrations were measured after 12 weeks of NCD, HFD, and HFD+PD treamtment. (A) Serum tota...
Background: Currently, combined therapy using herbs and synthetic drugs has become a feasible therap...
Obesity is characterized by lipid accumulation in distinct organs. Presently, fenofibrate is a commo...
A major obstacle compromising the successful application of many of the new targeted anticancer drug...
<p>DIO mice were treated with saline, control (Cont) ASO or FGFR4 ASO #2 at 50 mg/kg/week for 8 week...
<p>Recombinant muFGF21 (1 or 10 mg/kg, pink and red symbols respectively) or vehicle (green symbols)...
<p>Blood samples were drawn from the murine orbits. Concentrations of VEGF and bFGF are illustrated ...
<p>Ob/ob mice were treated with a specific Slc10a2 protein inhibitor, (AZD7806), or control vehicle ...
<p>WT and PPARα KO mice were on a high fat diet for 6 weeks and treated with fenofibrate (FF) or bil...
1<p>Two-way ANOVA and Tukey contrasts were performed to compare differences among the groups of LLC-...
(A) Body weight. (B) Body weight gain. (C) Subcutaneous and epididymal fat mass (g/100 g body weight...
<p><i>A:</i> Body weight gain relative to weight at day 0 for mice given different diets and treatme...
<p>Tactile threshold (A) and motor conduction latency of the sciatic nerves (B) in <i>db/m</i> and <...
The peroxisome proliferator-activated receptor alpha (PPARα) activator fenofibrate efficiently decre...
The peroxisome proliferator-activated receptor alpha (PPAR alpha) activator fenofibrate efficiently ...
Serum concentrations were measured after 12 weeks of NCD, HFD, and HFD+PD treamtment. (A) Serum tota...
Background: Currently, combined therapy using herbs and synthetic drugs has become a feasible therap...
Obesity is characterized by lipid accumulation in distinct organs. Presently, fenofibrate is a commo...
A major obstacle compromising the successful application of many of the new targeted anticancer drug...
<p>DIO mice were treated with saline, control (Cont) ASO or FGFR4 ASO #2 at 50 mg/kg/week for 8 week...
<p>Recombinant muFGF21 (1 or 10 mg/kg, pink and red symbols respectively) or vehicle (green symbols)...
<p>Blood samples were drawn from the murine orbits. Concentrations of VEGF and bFGF are illustrated ...
<p>Ob/ob mice were treated with a specific Slc10a2 protein inhibitor, (AZD7806), or control vehicle ...
<p>WT and PPARα KO mice were on a high fat diet for 6 weeks and treated with fenofibrate (FF) or bil...
1<p>Two-way ANOVA and Tukey contrasts were performed to compare differences among the groups of LLC-...
(A) Body weight. (B) Body weight gain. (C) Subcutaneous and epididymal fat mass (g/100 g body weight...