A diagram showing all proteins regulated in proton-irradiated BLM cells.

<p>The level of 17 proteins changed (>1.5×) in comparison with control. Thirteen proteins were upregulated (in black) and 4 were downregulated (in red). Here they are presented in four, not exclusive, groups: i) DNA repair and stress, ii) proliferation and survival control, iii) metabolic and iv) connected to motility and the cytoskeleton. ACTN 4 - α Actinin 4, Caprin-1 - Cytoplasmic activation/proliferation-associated protein-1, FAB-2 - Far upstream element binding protein 2, G3BP1 - RasGAP SH3-domain-binding protein 1, GADPH - Glyceraldehyde 3-phosphate dehydrogenase, MCM-7– Minichromosome Maintenance Protein 7, Moesin - Actin-regulatory protein, MVP - Major Vault Protein, PDCD6 - Programmed cell death 6, or apoptosis-linked gene-2, STRAP - Serine-threonine kinase receptor-associated protein, TIM - Triosephosphate isomerase, VCP – Transitional endoplasmic reticulum ATPase.