<p>Dashed boxes contain subjects that are infectious. All latent active, failure and treated/cured boxes are subdivided by drug sensitivity (sensitive; multi-drug resistant, MDR; isoniazid monoresistant, INHr). As illustrated in the inset, MDR may arise directly from susceptible strains or (with increased probability) from INHr-TB.</p
<p>The 23 samples were from a cohort of 311 participants. The heat map shows samples represented in ...
*Locations of individuals with no specimens submitted from a clinic, indicating the location of the ...
To describe factors associated with multidrug-resistant (MDR), including extensively-drug-resistant ...
<p>Diagram showing the detection of non-MDR-TB and MDR-TB. Individuals with MDR-TB transition throug...
<p><i>Definition of abbreviation</i>: MDR TB = multidrug resistant tuberculosis; MODS = microscopic-...
<p>Diagram shows the distribution of multidrug-resistant/pre-extensively drug-resistant and extensiv...
<p>The diagram shows how resistance can occur in the presence of PrEP. The boxes represent different...
<p>MDR-TB is tuberculosis resistant to at least isoniazid and rifampin; XDR-TB is tuberculosis resis...
<p>DST, drug susceptibility testing; DSTB, drug-susceptible tuberculosis; TB, tuberculosis.</p
<p>Projected trajectories for multi-drug resistant (MDR) (A, C) and INH-resistance (INHr) (B, D) cas...
<p>Boxes represent health states, arrows represent population flow between health states, red arrows...
<p>For each strain, exposure to INH was done in duplicate, in two independent assays - processes A a...
<p>Includes one null PSQ sample result (denoted as 'a'). R: Resistant, S: Susceptible, and I: Indete...
<p>RIF = Rifampicin</p><p>INH = Isoniazid</p><p>RIF<sup>R</sup> INH<sup>R</sup> = MDR-TB.</p><p>RIF<...
<p><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0046481#s3" target="_blank"...
<p>The 23 samples were from a cohort of 311 participants. The heat map shows samples represented in ...
*Locations of individuals with no specimens submitted from a clinic, indicating the location of the ...
To describe factors associated with multidrug-resistant (MDR), including extensively-drug-resistant ...
<p>Diagram showing the detection of non-MDR-TB and MDR-TB. Individuals with MDR-TB transition throug...
<p><i>Definition of abbreviation</i>: MDR TB = multidrug resistant tuberculosis; MODS = microscopic-...
<p>Diagram shows the distribution of multidrug-resistant/pre-extensively drug-resistant and extensiv...
<p>The diagram shows how resistance can occur in the presence of PrEP. The boxes represent different...
<p>MDR-TB is tuberculosis resistant to at least isoniazid and rifampin; XDR-TB is tuberculosis resis...
<p>DST, drug susceptibility testing; DSTB, drug-susceptible tuberculosis; TB, tuberculosis.</p
<p>Projected trajectories for multi-drug resistant (MDR) (A, C) and INH-resistance (INHr) (B, D) cas...
<p>Boxes represent health states, arrows represent population flow between health states, red arrows...
<p>For each strain, exposure to INH was done in duplicate, in two independent assays - processes A a...
<p>Includes one null PSQ sample result (denoted as 'a'). R: Resistant, S: Susceptible, and I: Indete...
<p>RIF = Rifampicin</p><p>INH = Isoniazid</p><p>RIF<sup>R</sup> INH<sup>R</sup> = MDR-TB.</p><p>RIF<...
<p><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0046481#s3" target="_blank"...
<p>The 23 samples were from a cohort of 311 participants. The heat map shows samples represented in ...
*Locations of individuals with no specimens submitted from a clinic, indicating the location of the ...
To describe factors associated with multidrug-resistant (MDR), including extensively-drug-resistant ...