GLA and CpG combine to enhance the protective efficacy of ID93.

<p>Mice were immunized and challenged with a low dose of aerosolized <i>M.tb.</i> (A) four or (B) twelve weeks later. <i>M.tb.</i> burdens in the lungs were determined four weeks after infection. Statistically significant differences between vaccinated groups were determined by ANOVA using the Bonferroni correction for multiple comparisons. Data are representative of three experiments with similar results with seven animals per group.