<p>Shown are the first 100 generations (200 in case of ) of 80 mutations that got fixed. The red line indicates the average mean selection coefficient, trajectories in grayscale indicate mean selection coefficients for individual mutations.</p
<p>A: Average number of mutations per passage in experiments with NVP (experimental set-ups C, D, E ...
<p>Solid curves and points show the probability of fixation of a mutation as a function of its selec...
<p>Three different scenarios were simulated: (A) dominance and selection are different in every gene...
<p>(a) SFS generated under fluctuating conditions. The proportion of mutations with positive and neg...
<p>Most synonymous mutations (<i>left panel</i>) have very low selection coefficients. For non-synon...
<p>orange: sweep from standing variation blue: sweep from a new mutation, blue: neutral model a: A c...
<p>The dark gray bars (left) represent the mean final fitness of populations that evolve under each ...
<p>Initial distributions (solid line) and fitness functions (dotted line) are plotted for various se...
<p>Shown are means across populations (+/−SE) over 36000 generations of selection in the four select...
<p>Point estimates for the selection coefficients for each transition mutation along the <i>pol</i> ...
<p>Fitness over time of all individuals in a population of size 100. The blue line is average popula...
This work is concerned with the historical progression, to fixation, of an allele in a finite popula...
The joint distribution of selection coefficients and mutation rates is a key determinant of the gene...
<p>Probability that phenotype is discovered (dotted lines) or is fixed (dashed lines) as a function...
<p>Dark grey are populations evolved in the benign environment and light grey are the populations ev...
<p>A: Average number of mutations per passage in experiments with NVP (experimental set-ups C, D, E ...
<p>Solid curves and points show the probability of fixation of a mutation as a function of its selec...
<p>Three different scenarios were simulated: (A) dominance and selection are different in every gene...
<p>(a) SFS generated under fluctuating conditions. The proportion of mutations with positive and neg...
<p>Most synonymous mutations (<i>left panel</i>) have very low selection coefficients. For non-synon...
<p>orange: sweep from standing variation blue: sweep from a new mutation, blue: neutral model a: A c...
<p>The dark gray bars (left) represent the mean final fitness of populations that evolve under each ...
<p>Initial distributions (solid line) and fitness functions (dotted line) are plotted for various se...
<p>Shown are means across populations (+/−SE) over 36000 generations of selection in the four select...
<p>Point estimates for the selection coefficients for each transition mutation along the <i>pol</i> ...
<p>Fitness over time of all individuals in a population of size 100. The blue line is average popula...
This work is concerned with the historical progression, to fixation, of an allele in a finite popula...
The joint distribution of selection coefficients and mutation rates is a key determinant of the gene...
<p>Probability that phenotype is discovered (dotted lines) or is fixed (dashed lines) as a function...
<p>Dark grey are populations evolved in the benign environment and light grey are the populations ev...
<p>A: Average number of mutations per passage in experiments with NVP (experimental set-ups C, D, E ...
<p>Solid curves and points show the probability of fixation of a mutation as a function of its selec...
<p>Three different scenarios were simulated: (A) dominance and selection are different in every gene...
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