<p>CD18 treated with GRN163L (GRN) or with no drug (CTR) were harvested at the end of the growth curve presented in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0085155#pone-0085155-g003" target="_blank">Figure 3</a>. Cells were fixed and stained with antibodies against TRF2 (green) and γ-H2AX (red) and were counter-stained with DAPI (blue). Images were visualized on a confocal microscope (Zeiss 510 Meta Confocal Laser Scanning Microscope). Three representative images of each sample are shown.</p
<p>SK-N-MC cells were exposed to cisplatinum or doxorubicin for 1 hour and then resuspended in drug ...
<p>CRL 1687cells were injected subcutaneously to nude athymic mice, which were treated three times a...
<p>TRF blots of untreated (left), AZT-treated (right) HT29 cells. PDL at which TRF was analyzed is s...
<p>Cells were treated every 2–3 days with no drug (CTR), mismatch oligo (MIS) or GRN163L (GRN). A–B)...
<p><b>A</b>. Representative micrograph images of cells from the telomerase-positive cell line HeLa a...
A-B Mean telomere fluorescence and percentage of short telomeres in whole lung (A) and in ATII cells...
<p>a. SK-N-MC, MCF-7 and K562 were exposed to 5uM of GRN163. Telomerase activity was assessed by the...
<p>(A) Graph evidence the relative TRT activity of DPSCs cultured in 1.25% HS medium, 10% FBS and 1....
<p>(<b>A</b>) Immunostaining-FISH images of WT.1 cells showing co-localization between telomerase RN...
<p>(A) Blue-stained nuclear DNA with punctate red fluorescence indicating telomeres hybridized to th...
A-E Mean telomere fluorescence and percentage of short telomeres in whole lung (A), in ATII cells (B...
<p>(<b>A</b>) Total protein extracts prepared from WI-38 cells transfected with control siRNA (lane ...
A-E Mean telomere fluorescence and percentage of short telomeres in whole lung (A), in ATII cells (B...
<p>(A) Control (C) and HHS-affected (S2) primary fibroblast cultures (established at the ages of 30 ...
<p>(A) Representative immunofluorescent image of telomeres (depicted by small white circles) using f...
<p>SK-N-MC cells were exposed to cisplatinum or doxorubicin for 1 hour and then resuspended in drug ...
<p>CRL 1687cells were injected subcutaneously to nude athymic mice, which were treated three times a...
<p>TRF blots of untreated (left), AZT-treated (right) HT29 cells. PDL at which TRF was analyzed is s...
<p>Cells were treated every 2–3 days with no drug (CTR), mismatch oligo (MIS) or GRN163L (GRN). A–B)...
<p><b>A</b>. Representative micrograph images of cells from the telomerase-positive cell line HeLa a...
A-B Mean telomere fluorescence and percentage of short telomeres in whole lung (A) and in ATII cells...
<p>a. SK-N-MC, MCF-7 and K562 were exposed to 5uM of GRN163. Telomerase activity was assessed by the...
<p>(A) Graph evidence the relative TRT activity of DPSCs cultured in 1.25% HS medium, 10% FBS and 1....
<p>(<b>A</b>) Immunostaining-FISH images of WT.1 cells showing co-localization between telomerase RN...
<p>(A) Blue-stained nuclear DNA with punctate red fluorescence indicating telomeres hybridized to th...
A-E Mean telomere fluorescence and percentage of short telomeres in whole lung (A), in ATII cells (B...
<p>(<b>A</b>) Total protein extracts prepared from WI-38 cells transfected with control siRNA (lane ...
A-E Mean telomere fluorescence and percentage of short telomeres in whole lung (A), in ATII cells (B...
<p>(A) Control (C) and HHS-affected (S2) primary fibroblast cultures (established at the ages of 30 ...
<p>(A) Representative immunofluorescent image of telomeres (depicted by small white circles) using f...
<p>SK-N-MC cells were exposed to cisplatinum or doxorubicin for 1 hour and then resuspended in drug ...
<p>CRL 1687cells were injected subcutaneously to nude athymic mice, which were treated three times a...
<p>TRF blots of untreated (left), AZT-treated (right) HT29 cells. PDL at which TRF was analyzed is s...