Determination of clonogenic survival and sub-G1 DNA content in SPR+ vs SPR- strains post-UVC.

<p><b>A</b>) Clonogenic survival in response to various doses of UVC was calculated as the number of surviving colonies (containing at least 50 cells) for irradiated cells relative to mock-irradiated counterparts. Values represent the mean +/− SEM of four independent experiments. <b>B</b>) Percentage of sub-G1 cells at different times after exposure to 10 J/m² of UVC in melanoma cell lines. Representative cell cycle profiles are shown for the SPR-deficient strain WM983B at 0 h and 72 h (top). Values represent the mean +/− SEM of three independent experiments.