Correlation between the estimated glomerular filtration rate and extent of interstitial fibrosis.

<p><b>A</b>. Best-fit slope of the linear regression between eGFR and extent of fibrosis. <b>B</b>, <b>C</b>, <b>D</b>. Best-fit slope of the linear regression between eGFR and extent of fibrosis in glomerular disease (B), tubular disease (C), and vascular disease (D). <b>E</b>. Histogram of the distribution of the extent of interstitial fibrosis according to the type of kidney disease. The percentages of interstitial fibrosis are expressed as the mean ± sem. *p<0.05 compared to glomerular disease, using Student's T test; the Mann-Whitney test was used for the glomerular vs. non specific lesions comparison. Glom: glomerular diseases; Tub-Int: tubular and/or interstitial diseases; Vasc: vascular diseases; Non-spe: non-specific.