<p>Cells transfected with A455E cDNA were treated either with MG132, a more general inhibitor (n = 6) (<b>A, B</b>), or the more specific inhibitor of proteasomes, PS341 (n = 2) (<b>C</b>). Note that in both cases, proteasome inhibition caused an increase in both the immature B and mature C bands of A455E.</p
Molecular chaperones and the ubiquitin-proteasome pathway are known to participate in the quality co...
<p>(a) Western blot analysis of capsid protein subunits in cell lysates using the B1 antibody at 18 ...
<p>(A) Western blot analysis of HEK cells transfected with APP-Cit followed by 6 h treatment with in...
<p>(A) To facilitate drug permeability or accumulation, <i>erg6Δ</i> and <i>pdr5Δ</i> strains were g...
<p>(A) SW480 cells stably expressing GFP-TNKS1 were treated with DMSO, G007-LK or MG132 alone or in ...
<p><b>A and B.</b> HEK293 cells were transfected with FLAG-GCH1 or empty vector (control) for 2 days...
<p>(A) Experimental setup. Proliferating HEL fibroblasts and the indicated knock-down derivatives we...
The proteasome is an intracellular protease complex consisting of the 20S catalytic core and its ass...
<p>Cos7 cells were transfected with A455E cDNA and treated with cycloheximide (25 µg/ml) for the ind...
<p><b>A</b>. ULK1 mediates p-S409 of p62 upon MG132 treatment. HEK 293T cells transfected with empty...
The ubiquitin-proteasome system is an important proteolytic pathway implicated in the formation of n...
SummaryThe ubiquitin-proteasome system is essential for maintaining protein homeostasis. However, pr...
<p><b>A</b>: Chymotrypsin-like, caspase-like, and trypsin-like activities were measured in the lysat...
<p><b>A and B.</b> Analysis of the effect of various proteolytic inhibitors on C protein accumulatio...
<p>(<b>A</b>) Representative Western blot analysis of CPE protein levels in N2A cells transfected wi...
Molecular chaperones and the ubiquitin-proteasome pathway are known to participate in the quality co...
<p>(a) Western blot analysis of capsid protein subunits in cell lysates using the B1 antibody at 18 ...
<p>(A) Western blot analysis of HEK cells transfected with APP-Cit followed by 6 h treatment with in...
<p>(A) To facilitate drug permeability or accumulation, <i>erg6Δ</i> and <i>pdr5Δ</i> strains were g...
<p>(A) SW480 cells stably expressing GFP-TNKS1 were treated with DMSO, G007-LK or MG132 alone or in ...
<p><b>A and B.</b> HEK293 cells were transfected with FLAG-GCH1 or empty vector (control) for 2 days...
<p>(A) Experimental setup. Proliferating HEL fibroblasts and the indicated knock-down derivatives we...
The proteasome is an intracellular protease complex consisting of the 20S catalytic core and its ass...
<p>Cos7 cells were transfected with A455E cDNA and treated with cycloheximide (25 µg/ml) for the ind...
<p><b>A</b>. ULK1 mediates p-S409 of p62 upon MG132 treatment. HEK 293T cells transfected with empty...
The ubiquitin-proteasome system is an important proteolytic pathway implicated in the formation of n...
SummaryThe ubiquitin-proteasome system is essential for maintaining protein homeostasis. However, pr...
<p><b>A</b>: Chymotrypsin-like, caspase-like, and trypsin-like activities were measured in the lysat...
<p><b>A and B.</b> Analysis of the effect of various proteolytic inhibitors on C protein accumulatio...
<p>(<b>A</b>) Representative Western blot analysis of CPE protein levels in N2A cells transfected wi...
Molecular chaperones and the ubiquitin-proteasome pathway are known to participate in the quality co...
<p>(a) Western blot analysis of capsid protein subunits in cell lysates using the B1 antibody at 18 ...
<p>(A) Western blot analysis of HEK cells transfected with APP-Cit followed by 6 h treatment with in...
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