Survey of microbial communities residing in breast tissue from breast cancer patients.

<p><b>A</b>) Phylum level distribution of microbial communities comparing paired normal adjacent (“paired normal”) and breast cancer tissue from 20 patients with ER-positive breast cancer (n = 20). Each bar represents 100% of the bacteria detected in a given sample. <b>B</b>) Combined distribution at the phylum level in paired normal and breast tumor tissue (n = 20). <b>C</b>) Number of OTUs found in each community (n = 20). <b>D</b>) Analysis of OTUs with differential abundance between paired normal and tumor tissue (n = 20). <b>E</b>) Correlation of relative abundances of <i>M. radiotolerans</i> and <i>S. yanoikuyae</i> (n = 20). <b>F</b>) Relative abundances of commonly found skin bacteria (n = 20). p-values from Student’s paired t-test are shown, with P<0.05 considered significant. Error bars represent mean ± s.e.m.