Invasive hemodynamic analysis of 6 and 10 weeks after AAB in wild-type and DPP4-deficient rats.

<p>Values are means ± SE (n = 8) MAP : mean arterial pressure, HR : heart rate, LVSP : left ventricular systolic pressure, LVEDP : left ventricular end-diastolic pressure, DP : development pressure, +dP/dt and −dP/dt : maximal slope of the systolic pressure increment and diastolic pressure decrement, respectively, Ves : end-systolic volume, Ved : end-diastolic volume, SV : stroke volume, EF : ejection fraction, ESPVR : end-systolic pressure–volume relation, and EDPVR : end-diastolic pressure–volume relation.</p><p>p<0.05 vs. wild-type 6 week sham,</p><p>^# p<0.05 vs. wild-type 6 week AAB,</p><p>^@ p<0.05 vs. wild-type 10 week sham,</p><p>^& p<0.05 vs. wild-type 10 week AAB,</p><p>p<0.05 vs. DPP4 deficiency 6 week sham.