Repression of <i>CHD5</i> promoter activity by DNA methylation.

<p>A set of reporter constructs of methylated or mock-methylated fragments of the –560 to –240 region were measured for luciferase activity in K-562 cells. The relative Luc activities of methylated and mock <i>CHD5</i> promoters were normalized to Renilla luciferase activity. All data are presented as mean ± SD. P<0.001 was considered statistically significant (**).