<p>Relative gene expression levels in the islets isolated before (<b>A</b>) and after 5-week HFD feeding (<b>B</b>). Gene expression levels were normalized to <i>Gapdh</i>, and the normalized expression levels in SDG-P mice (closed column) were expressed as relative values to those in SDG-R mice (open column). Mean ± SEM (n = 7–9). *<i>p</i><0.05, <i>versus</i> SDG-R mice.</p
<p>Relative mRNA levels for <i>Gfp</i> (A) <i>glucagon</i> (B), <i>insulin1</i> (C), and <i>Arx</i> ...
<p>Values represent mean ± SEM of copy number adjusted by normalization factor (NF) per 100 ng of cD...
<p>Expression levels of the indicated 7 candidates localized within the diabesity-QTL <i>Nob3</i> on...
<p>Stereomicroscopic images of the islets isolated before (<b>A</b>) and after 5-week HFD feeding (<...
<p>(A) Immunohistochemistry with anti-PECAM1 or anti-VEGF-A antibodies in pancreatic sections from H...
<p>A: mRNA level of 5-HT<sub>2C</sub>R was significantly higher in pancreatic islets of db/db mice c...
<p>A. Gene expression levels of mouse islets relative to <i>Perk<sup>+/+</sup></i>. Mice are postnat...
<p>Data are normalized for <i>ActB</i> and expression in liver (from 12 weeks old mice) is set as 1,...
<p>Gene expression was evaluated by qRT-PCR. (a) <i>INS1</i> expression declined in both groups of m...
<p>(A) Body weight (BW), (B) glycemia, (C) insulinemia, (D) cholesterolemia, (E) plasma fatty acids ...
<p>(A). Representative Western blots (panel 1,3) and PCR analyzes (panel 2,4) of AIF expression in i...
<p>(<b>A–B</b>) Primary islets were isolated from male (<b>A</b>) JNK1<sup>−/−</sup> (n = 5) or (<b>...
<p>(A) Glucose-stimulated insulin secretion from isolated islets (<i>n</i> = 10, *<i>p</i><0.05). (B...
<p>Mean ± SEM (n = 5–6).</p><p><sup>a</sup> Five weeks of age.</p><p><sup>b</sup> Ten weeks of age.<...
<p><i>Gene/Cyclophilin</i> mRNA ratio were measured by real-time PCR using islet cDNA from 10-week-o...
<p>Relative mRNA levels for <i>Gfp</i> (A) <i>glucagon</i> (B), <i>insulin1</i> (C), and <i>Arx</i> ...
<p>Values represent mean ± SEM of copy number adjusted by normalization factor (NF) per 100 ng of cD...
<p>Expression levels of the indicated 7 candidates localized within the diabesity-QTL <i>Nob3</i> on...
<p>Stereomicroscopic images of the islets isolated before (<b>A</b>) and after 5-week HFD feeding (<...
<p>(A) Immunohistochemistry with anti-PECAM1 or anti-VEGF-A antibodies in pancreatic sections from H...
<p>A: mRNA level of 5-HT<sub>2C</sub>R was significantly higher in pancreatic islets of db/db mice c...
<p>A. Gene expression levels of mouse islets relative to <i>Perk<sup>+/+</sup></i>. Mice are postnat...
<p>Data are normalized for <i>ActB</i> and expression in liver (from 12 weeks old mice) is set as 1,...
<p>Gene expression was evaluated by qRT-PCR. (a) <i>INS1</i> expression declined in both groups of m...
<p>(A) Body weight (BW), (B) glycemia, (C) insulinemia, (D) cholesterolemia, (E) plasma fatty acids ...
<p>(A). Representative Western blots (panel 1,3) and PCR analyzes (panel 2,4) of AIF expression in i...
<p>(<b>A–B</b>) Primary islets were isolated from male (<b>A</b>) JNK1<sup>−/−</sup> (n = 5) or (<b>...
<p>(A) Glucose-stimulated insulin secretion from isolated islets (<i>n</i> = 10, *<i>p</i><0.05). (B...
<p>Mean ± SEM (n = 5–6).</p><p><sup>a</sup> Five weeks of age.</p><p><sup>b</sup> Ten weeks of age.<...
<p><i>Gene/Cyclophilin</i> mRNA ratio were measured by real-time PCR using islet cDNA from 10-week-o...
<p>Relative mRNA levels for <i>Gfp</i> (A) <i>glucagon</i> (B), <i>insulin1</i> (C), and <i>Arx</i> ...
<p>Values represent mean ± SEM of copy number adjusted by normalization factor (NF) per 100 ng of cD...
<p>Expression levels of the indicated 7 candidates localized within the diabesity-QTL <i>Nob3</i> on...