SET knockdown by siRNA or over-expression in inducing apoptosis by As₄S₄ in NB4-R1 cells using Annexin V-FITC/PI double staining and flow cytometry analysis.

<p>(A) GFP detection of transfection efficiency through fluorescence microscopy. SET knockdown by shRNA (a, b), SET over-expression (c, d). (B) SET protein down-regulated by shRNA-SET (C) SET protein over-expression by SET expression plasmid. (D) PML-RARα and PP2A protein expression in cells by shRNA-SET. (E) PML-RARα and PP2A protein expression in cells by using SET expression plasmid. (F) Annexin V-FITC/PI double staining and flow cytometry analysis.