Correlation of fat or muscle fraction, determined by quantitative MRI, with clinical scores.

<p>(<b>A</b>) Correlation between age of the patient and average fat fraction of the thigh (p<0.05, R² = 0.15). (<b>B</b>) Average fat fraction of the thigh and FSHD duration are highly correlated (p<0.0001, R² = 0.54). (<b>C</b>) Fat fraction highly correlates with the radiological Lamminen score of the corresponding muscle (p<0.0001, R² = 0.70). (<b>D</b>) Quantitative fat fraction of lower limb correlates with patients Ricci score (p<0.0001, R² = 0.90). Fat fraction starts to increase above normal levels at Ricci score 2. The high standard deviation depicted in the error bars signifies the large variation in fat fraction determined in the limb and the appointed Ricci score. (<b>E</b>) Correlation between muscle fraction (1-fat fraction) and force of quadriceps and hamstring muscle groups (p<0.0001 and R² = 0.76).