Figure 4

<p>A–D: Enzyme activities and protein levels of 3β-HSD1 (A,C), P450c17 (B,D), in fetal testis from GD20.5 following in utero PFOS exposures. Pregnant dams were gavaged with 0, 5, or 20 mg/kg PFOS from GD11 to GD19. The enzyme activities were measured as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0078888#s2" target="_blank">Materials and Methods</a>. Data are presented as mean ± SEM (n = 5∼6). E–H: quantification of mother serum (n = 3) , male pup liver cholesterol (n = 8) and testicular LDL or HDL (n = 8). *^,**^,*** indicates significant difference compared to control (PFOS 0 mg/kg) was shown at, <i>P<0.05</i>, <i>P<0.01</i>, <i>P<0.001</i>, respectively.