Schematic representation of motif structures and other characteristic features of proteins encoded by the novel genes analyzed in the present study.

<p>Boxes with names of motifs represent those identified by Pfam. Boxes with A in MSI60 represent the region composed of poly alanine residues. TTTIHNSHSK repeats and RIV region are newly found in the present study. The number at the right of each sequence represents that of the amino acid residue from the N terminus in the molecule. Black and white arrowheads represent the positions of putative <i>O</i>- and <i>N</i>-linked glycosylation sites predicted by NetOGlyc and NetNGlyc, respectively. Abbreviations used are: signal, signal peptide; TIL, trypsin inhibitor like cysteine rich domain; TSP 1, thrombospondin type 1 domain; TM helix, transmembrane helix; Gal Lectin, galactose binding lectin domain; VMD, von Willebrand factor type A domain. Cs in the 000204 and 000058 proteins represent cysteine residues. TTTIHNSHSK repeat in the 000098 protein means the repetitive sequence of TTIHNSHSK. The RIV region in the 000133 protein indicates the region rich in arginine, isoleucine and valine residues. Data for nacrein (accession no. BAA11940) and MSI60 (BAA20466) were cited from GenBank.