<p><b>A</b>) Structure of the pIgHSV40shCD5 targeting vector. The cDNA sequence for shCD5 was inserted as <i>Xho</i>I-<i>Apa</i>I in between the promoter and polyA sequence of the pIg vector and then isolated as ScaI-ApaLI fragment for oocyte injections. <b>B</b>) Western blot analysis of human CD5 immunoprecipitates from transgenic (shCD5EμTg) and non-transgenic mice (NonTg) sera. The anti-CD5 Cris-1 mAb coupled with CNBr-activated Sepharose beads was used as immunoprecipitating agent. Western blotting was then carried out using the Leu-1 mAb plus HRP-labeled anti-mouse Ig. As a positive control, purified rshCD5 (50 ng) was included. <b>C</b>) ELISA detection of shCD5 in sera from shCD5EμTg mice. Sera from transgenic (shCD5EμTg, white) and...
Objective To breed OVA-HBsAg transgenic mice regulated by Cre recombinase in order to provide a bett...
<p>A) Analysis of CIA induction in (DBA_B6)F1×shCD5EμTg mice and non-transgenic littermates. 7–8 wee...
<p>Immunoblot from red cell ghost preparations immunostained with anti-hRhAG (LA18.18), anti-RhD (LO...
Trabajo presentado al: "Roche/Nature Medicine 2011 Symposium on Cancer Immunology and Immunotherapy"...
CD5 is a lymphoid-specific transmembrane glycoprotein constitutively expressed on thymocytes and mat...
<p>(<b>A</b>) Schematic representation of the human CD4/CCR5 and cyclin T1 transgene constructs. E4/...
<p>(A), Schematic representation of the transgene construct of hPDCD5 cDNA under the control of the ...
This is an open-access article distributed under the terms of the Creative Commons Attribution Licen...
<p>(A) Schematic diagram of the optimized hDPP4 expression vector cassette. The optimized hDPP4 was ...
<p>(A) Expression levels of NS5A protein in liver tissues of NS5A-transgenic (Tg) and non-transgenic...
<p>Transgene expression was detected by Western Blot using polyclonal anti-H5N1 mouse sera and a goa...
AbstractThe absence of relevant animal models of chronic hepatitis B virus (HBV) infection has hampe...
<p>(A–B) Schematic representation of the bFcRn and anti-HAV mAb constructs for microinjection. Chick...
<p><b>A.</b> Schematic of generating vector-transduced HSPC-transplanted hu-BLT mouse. NSG mouse is ...
<p>(A) Experimental design for immunization of humanized mice with the HCMV strains. DC generated fr...
Objective To breed OVA-HBsAg transgenic mice regulated by Cre recombinase in order to provide a bett...
<p>A) Analysis of CIA induction in (DBA_B6)F1×shCD5EμTg mice and non-transgenic littermates. 7–8 wee...
<p>Immunoblot from red cell ghost preparations immunostained with anti-hRhAG (LA18.18), anti-RhD (LO...
Trabajo presentado al: "Roche/Nature Medicine 2011 Symposium on Cancer Immunology and Immunotherapy"...
CD5 is a lymphoid-specific transmembrane glycoprotein constitutively expressed on thymocytes and mat...
<p>(<b>A</b>) Schematic representation of the human CD4/CCR5 and cyclin T1 transgene constructs. E4/...
<p>(A), Schematic representation of the transgene construct of hPDCD5 cDNA under the control of the ...
This is an open-access article distributed under the terms of the Creative Commons Attribution Licen...
<p>(A) Schematic diagram of the optimized hDPP4 expression vector cassette. The optimized hDPP4 was ...
<p>(A) Expression levels of NS5A protein in liver tissues of NS5A-transgenic (Tg) and non-transgenic...
<p>Transgene expression was detected by Western Blot using polyclonal anti-H5N1 mouse sera and a goa...
AbstractThe absence of relevant animal models of chronic hepatitis B virus (HBV) infection has hampe...
<p>(A–B) Schematic representation of the bFcRn and anti-HAV mAb constructs for microinjection. Chick...
<p><b>A.</b> Schematic of generating vector-transduced HSPC-transplanted hu-BLT mouse. NSG mouse is ...
<p>(A) Experimental design for immunization of humanized mice with the HCMV strains. DC generated fr...
Objective To breed OVA-HBsAg transgenic mice regulated by Cre recombinase in order to provide a bett...
<p>A) Analysis of CIA induction in (DBA_B6)F1×shCD5EμTg mice and non-transgenic littermates. 7–8 wee...
<p>Immunoblot from red cell ghost preparations immunostained with anti-hRhAG (LA18.18), anti-RhD (LO...