Tissue levels of aberrantly methylated genes.
- Russell I. Heigh (510896)
- Tracy C. Yab (510897)
- William R. Taylor (162523)
- Fareeda T. N. Hussain (510898)
- Thomas C. Smyrk (144839)
- Douglas W. Mahoney (510899)
- Michael J. Domanico (510900)
- Barry M. Berger (510901)
- Graham P. Lidgard (510902)
- David A. Ahlquist (510903)
Publication date
January 2014
DOIAbstract
<p>Tissue levels of methylated <i>BMP3 (mBMP3)</i> and <i>NDRG4 (mNDRG4)</i> genes are compared in normal colorectal mucosa, n = 20 unique control patients, and sessile serrated polyps (SSP), n = 20 unique case patients. Marker levels are normalized to <i>β-actin</i> (a marker of total human DNA) and expressed in relative units. Levels were substantially and significantly higher in SSP than normal colon for both <i>mBMP3</i> (p<0.0001) and <i>mNDRG4</i> (p<0.0001).</p
Add to ORKG