Standardized hazard ratios associated with diastolic home blood pressure by category of conventional blood pressure.

<p>Systolic/diastolic thresholds for CBP were as follows: optimal, <120/<80 mm Hg; normal, 120–129/80–84 mm Hg; high-normal, 130–139/85–89 mm Hg; mild hypertension, 140–159/90–99 mm Hg; and severe hypertension, ≥160/≥100 mm Hg. When the systolic and diastolic blood pressures were in different categories, the participant was assigned to the higher category. The category prehypertension includes participants with normal and high-normal blood pressure, and the category hypertension includes participants with mild and severe hypertension. The number of people at risk and the number of events are given in <a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1001591#pmed-1001591-t003" target="_blank">Tables 3</a> and <a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1001591#pmed-1001591-t004" target="_blank">4</a>, respectively. HRs reflect the risk associated with a 5-mm Hg increase in home diastolic pressure. HRs were adjusted for cohort as a random effect and for sex, age, body mass index, smoking, total cholesterol, diabetes mellitus, and history of cardiovascular disease as fixed effects. Significance of the HRs: *<i>p</i><0.05; †<i>p</i><0.01; and ‡<i>p</i><0.001.