<p>The figure shows the western blot of one 3D tendon-construct over four time points shown(+/- tension).</p
In this thesis, we focus on novel proteins/mechanisms that regulate integrin-adhesion mediated mecha...
Integrins are a family of transmembrane proteins, involved in substrate recognition and cell adhesio...
Extracellular matrix fibrils of fibronectin (FN) are highly elastic, and are typically stretched thr...
<p>A) Effect of de-tensioning on integrin sub-unit α5, B) Effect of de-tensioning on integrin sub-un...
<p>Left panel (A, D, G, J): Effect of de-tensioning, mid panel (B, E, H, K): Effect of TGF-β1 on ten...
<p>Left panel (A, D, G, J): Effect of de-tensioning, mid panel (B, E, H, K): Effect of TGF-β1 on ten...
<p>Left panel (A, D): Effect of de-tensioning, mid panel (B, E): Effect of TGF-β1 on tensioned 3D te...
<div><p>Mechanical loading of tendon cells results in an upregulation of mechanotransduction signali...
<p>The 3D tendon-construct under static tension without TGF-β1 is set as baseline, all other conditi...
<p>Left panel (A, D, G, J): Effect of de-tensioning, mid panel (B, E, H, K): Effect of TGF-β1 on ten...
Mechanical tension is a critical determinant of cell growth, differentiation, apoptosis, migration, ...
<p>Summary of <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0086078#pone-008...
<p>A. Activated β1 integrin (detected using β1 antibody clone 9EG7) and actin (detected with fluores...
Tendon cells exist in a dense extracellular matrix and mechanical loading is important for the stren...
A proteomic analysis of engineered tendon formation under dynamic mechanical loading in vitroPreviou...
In this thesis, we focus on novel proteins/mechanisms that regulate integrin-adhesion mediated mecha...
Integrins are a family of transmembrane proteins, involved in substrate recognition and cell adhesio...
Extracellular matrix fibrils of fibronectin (FN) are highly elastic, and are typically stretched thr...
<p>A) Effect of de-tensioning on integrin sub-unit α5, B) Effect of de-tensioning on integrin sub-un...
<p>Left panel (A, D, G, J): Effect of de-tensioning, mid panel (B, E, H, K): Effect of TGF-β1 on ten...
<p>Left panel (A, D, G, J): Effect of de-tensioning, mid panel (B, E, H, K): Effect of TGF-β1 on ten...
<p>Left panel (A, D): Effect of de-tensioning, mid panel (B, E): Effect of TGF-β1 on tensioned 3D te...
<div><p>Mechanical loading of tendon cells results in an upregulation of mechanotransduction signali...
<p>The 3D tendon-construct under static tension without TGF-β1 is set as baseline, all other conditi...
<p>Left panel (A, D, G, J): Effect of de-tensioning, mid panel (B, E, H, K): Effect of TGF-β1 on ten...
Mechanical tension is a critical determinant of cell growth, differentiation, apoptosis, migration, ...
<p>Summary of <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0086078#pone-008...
<p>A. Activated β1 integrin (detected using β1 antibody clone 9EG7) and actin (detected with fluores...
Tendon cells exist in a dense extracellular matrix and mechanical loading is important for the stren...
A proteomic analysis of engineered tendon formation under dynamic mechanical loading in vitroPreviou...
In this thesis, we focus on novel proteins/mechanisms that regulate integrin-adhesion mediated mecha...
Integrins are a family of transmembrane proteins, involved in substrate recognition and cell adhesio...
Extracellular matrix fibrils of fibronectin (FN) are highly elastic, and are typically stretched thr...
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