Epigenetic changes predict molecular responses to _erulean induced pancreatitis (CIP).

<p>Schematic representation of ChIP-seq data showing H3K4Me3 enrichment for (<b>A</b>) <i>Ptgs2</i> and (<b>B</b>) <i>Rpik3</i>, which were uniquely enriched for H3K4Me3 in <i>Mist1^−/−</i> tissue but exhibit no change in gene expression. Arrows indicate peak differences. Bars under the graph depict the extent of the genes. Graphs represent qRT-PCR on whole pancreatic tissue from untreated or four hours of _erulean treatment in wild type (WT) and <i>Mist1^−/−</i> (M1-) mice (left; n = 3), or immediately after acinar cell isolation (n = 4; right).