The bioreducible star-shaped gene vector (POSS-(SS-PDMAEMA)<sub>8</sub>) with well-defined structure and relatively narrow molecular weight distribution was synthesized via atom transfer radical polymerization (ATRP) of (2-dimethylamino)ethyl methacrylate (DMAEMA) from a polyhedral oligomeric silsesquioxane (POSS) macroinitiator. POSS-(SS-PDMAEMA)<sub>8</sub> was composed of a biocompatible POSS core and eight disulfide-linked PDMAEMA arms, wherein the PDMAEMA chain length could be adjusted by controlling polymerization time. POSS-(SS-PDMAEMA)<sub>8</sub> can effectively bind pDNA into uniform nanocomplexes with appropriate particle size and zeta potential. The incorporation of disulfide bridges gave the POSS-(SS-PDMAEMA)<sub>8</sub> mater...
The field of tissue engineering (TE) is increasingly using biomaterial scaffolds which are augmented...
Poly(amido ethylenimine) polymers, a new type of peptidomimetic polymer, containing multiple disulfi...
Due to improved safety, low cost and high packing capacity, polymeric vectors have become a promisin...
ABSTRACT: The bioreducible star-shaped gene vector (POSS-(SS-PDMAE-MA)8) with well-defined structure...
Bioreducible, cationic linear poly(amino ether)s (PAEs) were designed as promising gene vectors. The...
Genetic modification (“transfection”) of mammalian cells using non-viral, synthetic agents such as p...
Bioreducible, cationic linear poly(amino ether)s (PAEs) were designed as promising gene vectors. The...
Core-shell type stars synthesized via atom transfer radical polymerization were used for the deliver...
A series of novel water-soluble, bioreducible poly(amido amine)s containing disulfide linkages in th...
A series of novel bioreducible poly(amido amine)s containing multiple disulfide linkages (SS-PAAs) w...
Star polymers with random and block copolymer arms made of cationic <i>N</i>,<i>N</i>′-dimethylamino...
The field of tissue engineering is increasingly recognizing that gene therapy can be employed for mo...
The field of tissue engineering is increasingly recognizing that gene therapy can be employed for m...
A series of novel water-soluble, bioreducible poly(amido amine)s (SS-PAAs) was synthesized by Michae...
Poly(amido ethylenimine) polymers, a new type of peptidomimetic polymer, containing multiple disulfi...
The field of tissue engineering (TE) is increasingly using biomaterial scaffolds which are augmented...
Poly(amido ethylenimine) polymers, a new type of peptidomimetic polymer, containing multiple disulfi...
Due to improved safety, low cost and high packing capacity, polymeric vectors have become a promisin...
ABSTRACT: The bioreducible star-shaped gene vector (POSS-(SS-PDMAE-MA)8) with well-defined structure...
Bioreducible, cationic linear poly(amino ether)s (PAEs) were designed as promising gene vectors. The...
Genetic modification (“transfection”) of mammalian cells using non-viral, synthetic agents such as p...
Bioreducible, cationic linear poly(amino ether)s (PAEs) were designed as promising gene vectors. The...
Core-shell type stars synthesized via atom transfer radical polymerization were used for the deliver...
A series of novel water-soluble, bioreducible poly(amido amine)s containing disulfide linkages in th...
A series of novel bioreducible poly(amido amine)s containing multiple disulfide linkages (SS-PAAs) w...
Star polymers with random and block copolymer arms made of cationic <i>N</i>,<i>N</i>′-dimethylamino...
The field of tissue engineering is increasingly recognizing that gene therapy can be employed for mo...
The field of tissue engineering is increasingly recognizing that gene therapy can be employed for m...
A series of novel water-soluble, bioreducible poly(amido amine)s (SS-PAAs) was synthesized by Michae...
Poly(amido ethylenimine) polymers, a new type of peptidomimetic polymer, containing multiple disulfi...
The field of tissue engineering (TE) is increasingly using biomaterial scaffolds which are augmented...
Poly(amido ethylenimine) polymers, a new type of peptidomimetic polymer, containing multiple disulfi...
Due to improved safety, low cost and high packing capacity, polymeric vectors have become a promisin...