SFN and DIM had distinct methylation gene targets in normal prostate epithelial cells and prostate cancer cells but high level of gene targets overlap within a single cell line.

<p>(A) Venn diagrams showing the number of genes that were differentially methylated in PrEC, LnCAP, and PC3 cells upon treatments with SFN or DIM compared to vehicle control. (B) Venn diagrams showing the number of differentially methylated gene targets of SFN and DIM within each cell line.