ARP2 expression induces apoptosis in CHO cells.

<p>(<b>A</b>) Western blots detected expression of β-gal-V5 (112 kDa) and ARP2-V5 (54 kDa) in total cell lysates. (<b>B</b>) Normalized cell viability% of controls was assessed using MTT assays with 2×10⁴ cells cultured in the absence of serum or transfected with <i>arp2</i> cDNA. Viability of these two treatment groups were assayed at 16, 24, 48, and 72 h timepoints. (<b>C</b>) Normalized cell viability% of controls was assessed using a trypan blue exclusion method. Cells were cultured in the absence of serum or transfected with <i>arp2</i> cDNA and assayed at 16, 24, 48, and 72 h timepoints. Mean values are presented (n = 3, X ± S.E.M), ^#<i>p</i><0.05, *<i>p</i><0.01, ^¶<i>p</i><0.001, compared to control groups.