MICs of SM21 and amphotericin B against a range of <i>Candida</i> and other fungal species.

<p>AMB – amphotericin B. The MICs of SM21 against the <i>Candida</i> isolates tested ranged from 0.2 – 1.6 µg/ml, while the MICs of amphotericin B ranged from 0.2 – 0.8 µg/ml. The similar range of MICs suggested the comparable potency of SM21 and amphotericin B. For the other fungal species, lower susceptibility of SM21 against <i>A. fumigatus</i> was observed. Such trend was also observed for amphotericin B.