Effect of mast cell inhibition with DSCG on scar width and wound breaking strength.

<p>(a) Average scar width in mice treated with DSCG compared to PBS treated mice. H & E staining was used to measure scar with at 7, 14 and 21 days post-wounding in DSCG treated mice (black bars) and control mice (white bars). N = 5. *p<0.05. (b) Effect of DSCG treatment on wound breaking strength. Incisional wounds were prepared on the back of mice treated with DSCG (black bar) or PBS (white bar). N = 10 for both groups. Wounds were excised at day 14, and two skin strips per mouse were used from the upper and lower back of the mouse. Both strips were subjected to tensiometric analysis. The bars indicate the means of wound breaking strength in grams.