PBMC derived from G5–7 women secrete lower levels of IL-10, IL-1β and IL-6.

<p>PBMC (2×10⁵/well) were exposed to 6×10⁵ unopsonised IE or IE opsonised with 9% HI autologous plasma (IE-IgG). After 48 h, culture supernatants were quantified for (<b>A</b>) IL-10, (<b>B</b>) IL-1β, (<b>C</b>) IL-6 and (D) TNF using a commercial multi-plex assay. Cytokine production from resting PMBC was subtracted from IE induced cytokine to eliminate the contribution of constitutive cytokine production and data is presented on a log₁₀ scale. Comparison between three groups (G1, G2–4, G5–7) was achieved using a non-parametric One Way ANOVA: Kruskal-Wallis test and the Dunn's Multiple Comparison post-test. * p&lt;0.05, ** p&lt;0.01.