<p>ClustalW alignment <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0086482#pone.0086482-Larkin1" target="_blank">[40]</a> of the NS4A(1–48) coding sequence as found in the viral genome of DENV type 2 and following optimization for <i>E. coli</i> expression <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0086482#pone.0086482-Fath1" target="_blank">[21]</a>.</p
<p><sup>a</sup> The EDI-II protein sequences of strains of DENV1-4 were aligned. Single letter amino...
<p>Panel A provides a schematic representation of the DENV genome, divided into structural and nonst...
In viruses under strong pressure to minimize genome size, overlapping genes represent a fine strateg...
Alignment for_DENV-2 virus genome sequences (can be opened with any simple text editor for.txt, or w...
Alignment for_DENV-1 virus genome sequences (can be opened with any simple text editor for.txt, or w...
<p>A ClustalW2 multiple alignment of 5′ (A) and 3′ (B) NTR sequences of the prototypic representativ...
<p><b>(A)</b> Sequence variation of residues 828–848 and 883–900 of DENV1–4 and representative flavi...
<p>Positions of miRNA targets for brain-expressed mir-124 and mosquito-specific mir-1, mir-184, or m...
<p><b>A</b>. CHIKV genomic RNA diagram with the indicated conserved region targeted for viral suppre...
<p>The sequence interval between the 121<sup>th</sup> and 149<sup>th</sup> amino acid (marked with -...
<p>(A) Top: Amino acid sequence alignments of representative sequences of the C-termini of all 6 gen...
Dengue virus (DENV) infection causes the most prevalent arthropod-borne viral disease worldwide. App...
This report is the first to characterise the complete coding sequence of a dengue virus serotype 4 (...
<p>(<b>A</b>) <i>Schematic representation of the delta-NS1 DENV genome and helper cell lines employe...
<p>(A) A representation of the DENV2 NS5 constructs used in this study. The E domain upstream of ubi...
<p><sup>a</sup> The EDI-II protein sequences of strains of DENV1-4 were aligned. Single letter amino...
<p>Panel A provides a schematic representation of the DENV genome, divided into structural and nonst...
In viruses under strong pressure to minimize genome size, overlapping genes represent a fine strateg...
Alignment for_DENV-2 virus genome sequences (can be opened with any simple text editor for.txt, or w...
Alignment for_DENV-1 virus genome sequences (can be opened with any simple text editor for.txt, or w...
<p>A ClustalW2 multiple alignment of 5′ (A) and 3′ (B) NTR sequences of the prototypic representativ...
<p><b>(A)</b> Sequence variation of residues 828–848 and 883–900 of DENV1–4 and representative flavi...
<p>Positions of miRNA targets for brain-expressed mir-124 and mosquito-specific mir-1, mir-184, or m...
<p><b>A</b>. CHIKV genomic RNA diagram with the indicated conserved region targeted for viral suppre...
<p>The sequence interval between the 121<sup>th</sup> and 149<sup>th</sup> amino acid (marked with -...
<p>(A) Top: Amino acid sequence alignments of representative sequences of the C-termini of all 6 gen...
Dengue virus (DENV) infection causes the most prevalent arthropod-borne viral disease worldwide. App...
This report is the first to characterise the complete coding sequence of a dengue virus serotype 4 (...
<p>(<b>A</b>) <i>Schematic representation of the delta-NS1 DENV genome and helper cell lines employe...
<p>(A) A representation of the DENV2 NS5 constructs used in this study. The E domain upstream of ubi...
<p><sup>a</sup> The EDI-II protein sequences of strains of DENV1-4 were aligned. Single letter amino...
<p>Panel A provides a schematic representation of the DENV genome, divided into structural and nonst...
In viruses under strong pressure to minimize genome size, overlapping genes represent a fine strateg...