Melatonin suppression and lens transmittance at 480 nm light, in young and aged subjects.

<p>Lens transmittance (open circle, straight line) is significantly lower in older compared to young subjects (p<0.0001) whereas melatonin suppression (full circle, straight line) at 480 nm is not significantly different between aged and young. The predicted effect of a decrease in lens transmittance at 480 nm on melatonin suppression is shown in gray circle, dashed line. Prediction was made using Brainard et al. 2001 irradiance response curves. See <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0085837#pone.0085837.s003" target="_blank">File S1</a> for more details on the analytics of the prediction.