Gelsolin localization in cochlear hair cells of Eps8 knockout mice (<i>Eps8^tm1Ppdf/Eps8^tm1Ppdf</i>).

<p>Cochlear whole mounts from P8 mice were stained with antibody to gelsolin (green) and phalloidin (red) to detect actin. Right hand panels for OHC and IHC cells show merge of gelsolin and actin. Note the absence of IHC labeling. Gelsolin localizes to stereocilia of OHCs (domain D2) and is also detected outside of the stereocilia bundle in strial (D1) and neural (D3) domains of the apical hair cell surface. Gelsolin localization was not affected in the Eps8 knockout mice. Similar results were seen at P6 (data not shown). Scale bars: 10 µm.