Effect of cDDP pretreatment of NT2-D1 cells on sensitivity to cDDP and paclitaxel.

<p>NT2-D1 cells were exposed to various concentrations of cDDP for 2 days then cultured in drug free media for 4 days following which they were replated and exposed continuously to cDDP or paclitaxel to generate concentration-survival curves. Each data point presents the mean of at least 4 independent experiments each performed with triplicate cultures. Vertical bars, ±SEM.